Kaplan-Meier curves for overall stratified according to FLT3^ITD mutant level. (A) All patients, (B) NPM1^WT patients, (C) NPM1^MUT patients with ≥25% NPM1^MUT, (D) NPM1^MUTFLT3^ITD patients with ≥25% NPM1^MUT where FLT3^ITD mutant level has been adjusted to NPM1^MUT level. P value is for trend. ITD, FLT3^ITD; No., number; WT, wild-type.