Correlation of TP53 mutation load with cytogenetic subgroups and with immunophenotype. (A) For each patient, the mutation load was determined and correlated to the respective karyotype. The number of patients with the respective mutation load is shown in regard to cytogenetic aberrations. (B) The TP53 mutation load was determined in each patient and the obtained value was correlated to the respective immunophenotype. The number of patients with the respective mutation load is shown in regard to Burkitt-ALL, T-lineage ALL, or B-lineage ALL.