Figure 2
Figure 2. Hemostatic resuscitation as performed in Copenhagen, Denmark. The figure shows the phases from start of hemorrhage to control of bleeding (hemostasis). We initiate ratio 1:1:1 driven transfusion therapy of RBCs, FFP, and platelets during the initial phase of massive bleeding. VHA is performed on arrival, allowing for an early shift toward VHA-guided therapy subsequently. VHA is repeated during resuscitation. Simultaneously, tranexamic acid is administered according to the CRASH2 trial, and efforts are made to correct and reverse augmenting factors of coagulopathy and shock. *Antifibrinolytics may also be administered according to the VHA algorithm (Table 1). TXA, tranexamic acid; Hb, hemoglobin; VTE, venous thromboembolism.

Hemostatic resuscitation as performed in Copenhagen, Denmark. The figure shows the phases from start of hemorrhage to control of bleeding (hemostasis). We initiate ratio 1:1:1 driven transfusion therapy of RBCs, FFP, and platelets during the initial phase of massive bleeding. VHA is performed on arrival, allowing for an early shift toward VHA-guided therapy subsequently. VHA is repeated during resuscitation. Simultaneously, tranexamic acid is administered according to the CRASH2 trial, and efforts are made to correct and reverse augmenting factors of coagulopathy and shock. *Antifibrinolytics may also be administered according to the VHA algorithm (Table 1). TXA, tranexamic acid; Hb, hemoglobin; VTE, venous thromboembolism.

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