Figure 3
Figure 3. Characterization of CD19+ B cells in the lymph node suggests the cells resistant to removal are memory cells. Contour plots of cell subsets and MFI of CD38 on CD19+ cells from (A) iliac lymph nodes of controls, and (B) RTX-treated patients. Bar graphs of (C) lymph node CD27−IgD+CD19+ naïve B cells, (D) CD27+IgD+CD19+ memory B cells, (E) CD27hiCD38hiIgD−CD19+ plasma cells, (F) CD27+IgD−CD19+ memory B cells, and (G) CD27−IgD−CD19+ B cells. For all bar graphs, one symbol represents one individual, and the height of the bar represents the mean. (H) Detailed analysis of CD19loCD20lo cells alone in RTX-treated patients.

Characterization of CD19+ B cells in the lymph node suggests the cells resistant to removal are memory cells. Contour plots of cell subsets and MFI of CD38 on CD19+ cells from (A) iliac lymph nodes of controls, and (B) RTX-treated patients. Bar graphs of (C) lymph node CD27IgD+CD19+ naïve B cells, (D) CD27+IgD+CD19+ memory B cells, (E) CD27hiCD38hiIgDCD19+ plasma cells, (F) CD27+IgDCD19+ memory B cells, and (G) CD27IgDCD19+ B cells. For all bar graphs, one symbol represents one individual, and the height of the bar represents the mean. (H) Detailed analysis of CD19loCD20lo cells alone in RTX-treated patients.

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