AMCs are more prominent in MM BM and PB and express high CXCR7. (A) Representative images for gating of AMCs (CD31⁺/CD34⁺) and MNCs (CD31⁻/CD34⁻) populations (left), and diagram of expression of CXCR7 on each of these populations (right). (B) Presence of AMCs expressed as a percentage of total MNCs in the BM and PB of MM patients and normal subjects. (C) Presence of AMCs expressed as a percentage of total MNCs in the BM and PB of mice with and without MM1.S xenografts. (D) The expression of CXCR7 on AMCs from BM and PB isolated from MM patients and healthy subjects, normalized to mean fluorescence intensity of MNCs in each sample.