Survival in an intention-to-treat analysis by response category. (A) PFS and (B) OS. (C) PFS and (D) OS with respect to achievement of flow CR and induction therapy (VMP or VTP) received. CR, hematological CR; < CR, less than hematological CR; Flow-CR, immunophenotypic CR; < Flow-CR, less than immunophenotypic CR; MRD−, MRD negative, immunophenotypic CR; MRD+, MRD positive.