Figure 4
Figure 4. Arterial identity and Notch signal are enhanced in ncor2 morphants and fos overexpressed embryos. (A) The expression pattern of dll4 and ephrinB2a in the control, ncor2 morphants, and fos-overexpressed embryos at 24 hpf. (B) Cryosectioning and confocal imaging revealed the enlarged artery in ncor2 morphants and fos-overexpressed embryos at 36 hpf, compared with the controls. (C) The quantification of the diameter of the dorsal aorta shown in (B) (mean ± SEM, n = 12, *P < .05). (D) qPCR result demonstrated Notch targets her2, her5, her6, her9, and hey12 were increased in ncor2 morphants and fos-overexpressed embryos at 24 hpf. (mean ± SD, n = 3, *P < .05).

Arterial identity and Notch signal are enhanced in ncor2 morphants and fos overexpressed embryos. (A) The expression pattern of dll4 and ephrinB2a in the control, ncor2 morphants, and fos-overexpressed embryos at 24 hpf. (B) Cryosectioning and confocal imaging revealed the enlarged artery in ncor2 morphants and fos-overexpressed embryos at 36 hpf, compared with the controls. (C) The quantification of the diameter of the dorsal aorta shown in (B) (mean ± SEM, n = 12, *P < .05). (D) qPCR result demonstrated Notch targets her2, her5, her6, her9, and hey12 were increased in ncor2 morphants and fos-overexpressed embryos at 24 hpf. (mean ± SD, n = 3, *P < .05).

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