RUNX1 genome-wide occupancy in HSPCs as determined by ChIP-seq. (A) The 6370 RUNX1 ChIP-seq peaks with a an FDR <1% are shown in relation to the absolute distance of the TSS of known genes in kb. (B) Distribution of RUNX1 ChIP-seq peaks are grouped based on promoter defined as >3 kb upstream of TSS (10.8%), intron (44.3%), exon (5.7%), and intergenic (39.2%) regions. (C) The 500 peaks with the lowest FDR were submitted to the MEME suite. The top motifs are shown and given with E-values, the associated motif family, and the frequency of the motif found in the 500 peaks.