Xpo7 knockdown significantly disrupts erythroid terminal nuclear condensation. (A) Erythroblasts infected with control or Xpo7 shRNA imaged at 48 hours of culture. Cells were stained with DAPI and imaged at 100× using confocal fluorescent microscopy. (B) (Upper) Quantification of volume of nuclei, measured by calculation of area for each Z-stack slice of confocal images in A, and (Lower) average DAPI intensity per combined deconvoluted 2-dimensional image.