SOX11-PDGFA paracrine axis. SOX11 serves to transcriptionally regulate PDGFA. Secretion of PDGFA promotes angiogenesis to support lymphomagenesis. Inhibition of this pathway by agents such as imatinib mesylate may be an avenue for clinical trial investigation.

SOX11-PDGFA paracrine axis. SOX11 serves to transcriptionally regulate PDGFA. Secretion of PDGFA promotes angiogenesis to support lymphomagenesis. Inhibition of this pathway by agents such as imatinib mesylate may be an avenue for clinical trial investigation.

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