Figure 4
Figure 4. Protein interaction network summarizing all regulated proteins belonging to the GO-term “cytoskeleton organization.” From all 299 regulated proteins, only members of the GO-term “platelet degranulation” were searched for interactions using STRING,24 using a medium threshold. Potential PKA sites are highlighted with arrows and the corresponding colors indicate the time points which are regulated compared with 0-second iloprost treatment (dashed lines for downregulation). Upregulated phosphorylation sites are labeled in red and downregulated in blue. Estimated protein copy numbers are taken from Burkhart et al.8

Protein interaction network summarizing all regulated proteins belonging to the GO-term “cytoskeleton organization.” From all 299 regulated proteins, only members of the GO-term “platelet degranulation” were searched for interactions using STRING,24  using a medium threshold. Potential PKA sites are highlighted with arrows and the corresponding colors indicate the time points which are regulated compared with 0-second iloprost treatment (dashed lines for downregulation). Upregulated phosphorylation sites are labeled in red and downregulated in blue. Estimated protein copy numbers are taken from Burkhart et al.

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