Preexisting infiltrating CD8⁺T cells and normal marrow cellularity are sensitive predictors of clinical response to DLI therapy. (A) Correlation of marrow cellularity and CD8⁺ T-cell infiltrates for all patients before DLI. (B) ROC analysis for stratifying clinical response (responders and nonresponders) by either preexisting marrow cellularity ≤70% or CD8⁺ T-cell infiltrate ≥4%. (C) Combining criteria results in 100% sensitivity and specificity.