Figure 6
Figure 6. Interactions between MM plasma cells, TICs, and BMSCs. The interaction between BMSCs and mature MM plasma cells induces GDF15 secretion and enhances the self-renewal of MM CSCs by AKT, SOX2, and BMI-1. Subsequent production of mature tumor cells further promotes this process.

Interactions between MM plasma cells, TICs, and BMSCs. The interaction between BMSCs and mature MM plasma cells induces GDF15 secretion and enhances the self-renewal of MM CSCs by AKT, SOX2, and BMI-1. Subsequent production of mature tumor cells further promotes this process.

Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal