Figure 7
Figure 7. Effect of IL-17A neutralization on the MRLlpr/lpr autoimmune phenotype and on lifespan. The mean ± SE of proteinuria (A) and serum anti-dsDNA autoantibodies (B) of the differently treated groups of mice are shown. (C) A Kaplan-Meier survival analysis is shown; anti–IL-17A vs IgG2A: P = .0039; anti–IL-17A vs vehicle: P = .0006.

Effect of IL-17A neutralization on the MRLlpr/lpr autoimmune phenotype and on lifespan. The mean ± SE of proteinuria (A) and serum anti-dsDNA autoantibodies (B) of the differently treated groups of mice are shown. (C) A Kaplan-Meier survival analysis is shown; anti–IL-17A vs IgG2A: P = .0039; anti–IL-17A vs vehicle: P = .0006.

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