Serum levels of IL-18, IL-10, and IL-1β in ALPS and DALD patients. Levels of IL-18 (A), IL-10 (B), and IL-1β (C) in ALPS (black diamonds), DALD (black circles), and healthy controls (white triangles). The horizontal bars are the medians, the boxes indicate the interquartile range, and the dashed lines in A and B indicate the cutoff value for ALPS diagnosis. Differences were tested with the Mann-Whitney U test.