American Society of Hematology

Figure 2

BA induces inflammatory anemia and changes in erythroid parameters in WT, IL-6-KO, and Hamp-KO mice. Mice were injected with 5 × 108 particles of BA, and their hematological parameters were monitored with CBC over 6 weeks. (A) Hb, (B) RBC number, (C) reticulocytes number, (D) MCH, (E) MCV, and (F) CHr. Twelve mice for each genotype were analyzed per time point. Error bars represent SD. Each time point in IL-6-KO and Hamp-KO mice was compared with the same time point in WT mice. P values were calculated using unpaired, 2-tailed Student t test. *P < .05; **P < .01; ***P < .001.

BA induces inflammatory anemia and changes in erythroid parameters in WT, IL-6-KO, and Hamp-KO mice. Mice were injected with 5 × 10⁸ particles of BA, and their hematological parameters were monitored with CBC over 6 weeks. (A) Hb, (B) RBC number, (C) reticulocytes number, (D) MCH, (E) MCV, and (F) CHr. Twelve mice for each genotype were analyzed per time point. Error bars represent SD. Each time point in IL-6-KO and Hamp-KO mice was compared with the same time point in WT mice. P values were calculated using unpaired, 2-tailed Student t test. *P < .05; **P < .01; ***P < .001.

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