Clinical, pathologic, and radiographic features of GATA2 deficiency. (A) Hypocellular bone marrow with trilineage hypoplasia (36-year-old woman), bone marrow core biopsy hematoxylin and eosin stain. (B-D) Atypical megakaryocytes, small mononuclear (B), and dysplastic forms with separated nuclear lobes (B-D); taken from bone marrow core biopsies (B,C) and aspirate smear (D). (E) Cutaneous M abscessus infection and (F) skin biopsy AFB smear showing abundant mycobacteria. (G) Computed tomography scan of the chest showing the typical crazy paving pattern of PAP and (H) lung biopsy hematoxylin and eosin stain showing alveolar filling with lipoproteinaceous material. (I) Recalcitrant periungual warts, (J) perineal condyloma, and vulvar/anal intraepithelial neoplasia. (K) Panniculitis/erythema nodosum involving the anterior shins. (L) Computed tomography scan of the abdomen with multiple hypodense liver lesions (arrows) and (M) liver biopsy showing EBV-related spindle cell tumor with in situ hybridization of EBV-encoded messenger RNA using EBV probe antifluorescein antibody and bond polymer refine detection. (N) Unilateral lymphedema of the right lower extremity. (O) Magnetic resonance imaging of the brain with embolic infarcts in the right occipital and left parietal lobes (arrows) in the setting of culture-negative endocarditis.