Preserved expression of the integrins CD11a, CD11b, CD18, CD29, CD49d, and ITGB7 on trisomy 12 CLL cells. The expression of the integrins CD11a (A), CD11b (B), CD18 (C), CD29 (D), CD49d (E), and ITGB7 (F) were assessed on PB CLL cells and B cells from healthy age-matched controls. Uniquely among the main cytogenetic categories, CLL cells from patients with trisomy 12 had relatively preserved expression of these integrins, with levels comparable to healthy B cells in some patients. A comparable pattern was observed whether the data were analyzed by “% positive” or by median fluorescence intensity.