Eosinophils recruited in response to ova sensitization and challenge do not degranulate in response to PVM infection and do not support antiviral activity. (A) Total eosinophils in BAL fluid from ova-sensitized and ova-challenged, both virus-naïve and PVM-infected B6 mice. (B) Cell differentials from mice in A, as well as controls that were ova sensitized and PBS challenged. (C) No immunoreactive mEPX was detected in any BAL fluids from this group; n = 4 to 6 mice per time point. (D) No RNase activity was detected in any BAL fluids from this group; n = 4 to 6 mice per time point. (E) Virus recovery from ova-sensitized and ova- or PBS-challenged wild-type B6 mice (Figure 4A).