Figure 6
Figure 6. LMP2A expression associates with high MYC level, which inversely correlates with low p27kip1 levels. (A) Western blot analyses of cell cycle regulators in purified B cells from 3-week-old WT, LMP2A/λ-MYC+/+, LMP2A/λ-MYC+/S10A, LMP2A/λ-MYCS10A/S10A, λ-MYC+/+, λ-MYC+/S10A, and λ-MYCS10A/S10A mice. Cyclin A was used as an S-phase marker. Normalized levels of p27kip1 and MYC are shown as percentages to Gapdh (loading control). (B) Bar graphs demonstrating MYC and p27kip1 protein expression in B cells from 3-week-old mice from 2 independent experiments. Each bar represents combined data from 4 experiments, with data represented as the mean ± SD.

LMP2A expression associates with high MYC level, which inversely correlates with low p27kip1levels. (A) Western blot analyses of cell cycle regulators in purified B cells from 3-week-old WT, LMP2A/λ-MYC+/+, LMP2A/λ-MYC+/S10A, LMP2A/λ-MYCS10A/S10A, λ-MYC+/+, λ-MYC+/S10A, and λ-MYCS10A/S10A mice. Cyclin A was used as an S-phase marker. Normalized levels of p27kip1 and MYC are shown as percentages to Gapdh (loading control). (B) Bar graphs demonstrating MYC and p27kip1 protein expression in B cells from 3-week-old mice from 2 independent experiments. Each bar represents combined data from 4 experiments, with data represented as the mean ± SD.

Close Modal

or Create an Account

Close Modal
Close Modal