Figure 5
Figure 5. GO-203 suppresses FLT3, AKT, and ERK activation in MOLM-13 cells sensitive and resistant to midostaurin/PKC412. MOLM-13 (A) and MOLM-13/PKC412 (B) cells were left untreated (control) or treated with 4 μM GO-203 for 0.5 and 2 hours. Total cell lysates were analyzed by immunoblotting with the indicated antibodies.MOLM-13 (C) and MOLM-13/PKC412 (D) cells were left untreated (control) or treated with 4 μM GO-203 for 0.5 and 2 hours. Total cell lysates were analyzed by immunoblotting with the indicated antibodies.

GO-203 suppresses FLT3, AKT, and ERK activation in MOLM-13 cells sensitive and resistant to midostaurin/PKC412. MOLM-13 (A) and MOLM-13/PKC412 (B) cells were left untreated (control) or treated with 4 μM GO-203 for 0.5 and 2 hours. Total cell lysates were analyzed by immunoblotting with the indicated antibodies.MOLM-13 (C) and MOLM-13/PKC412 (D) cells were left untreated (control) or treated with 4 μM GO-203 for 0.5 and 2 hours. Total cell lysates were analyzed by immunoblotting with the indicated antibodies.

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