Bar plot representation of differential gene expression at different stages of human terminal erythroid differentiation. (A) Human. The greatest changes in differential gene expression were seen between the late basophilic to polychromatic and the polychromatic to orthochromatic (Ortho) stages. (B) Mouse. The greatest changes in differential gene expression were seen between proerythroblast to basophilic and polychromatic to Ortho erythroblast stages, with genes being downregulated predominating between both stage transitions.