Inhibition of GpIbα-VWF interactions restores vessel patency after occlusive thrombosis. (A) Representative immunohistological staining (of 5 mice) of the MCA 10 minutes after ATA treatment (injected 20 minutes after MCAo). Quantification of the relative areas (in percentage of the total MCA area) of the whole thrombus (B), the VWF-poor (C), and the VWF-rich areas (D) in mice brains 10 minutes after administration of either saline or ATA (n = 4 mice/group). ns, not significant.