Subgroup analyses of ABRs. Subgroup analyses results were consistent with the primary analyses, showing a reduction in bleeding rates in all prophylaxis subgroups compared with episodic therapy. Arm 1 was the only subgroup with a sufficient number of subjects to display results graphically. The box and whiskers represent the median, 25% to 75% range, and 10% to 90% range, respectively; circles represent individual subject outliers.