Versican expression in lymphoid malignancies and normal tissues. Tissue from a lymphoma and a myeloma TMA (see “Materials and methods”) was stained with antibodies recognizing a neo-epitope generated by cleavage of versican by ADAMTS1/4 (“cleaved versican”) and an antibody against the hyaluronan-binding domain of the versican protein core (“G1-domain”). Representative staining patters are shown for normal tissue (tonsils, lymph nodes [LN], BM), a panel of lymphomas (BL⁺: Burkitt lymphoma with a t(8;14), BL⁻: Burkitt lymphoma without a t(8;14)) and myeloma BM; FL, follicular lymphoma, MCL, mantle cell lymphoma, SLL, small lymphocytic lymphoma. Secondary-only and isotype staining controls are also shown. A summary of the TMA staining scores is provided as supplemental Tables 2 and 3.