![Figure 1. PLZF expression identifies PTCL arising from innate-like mucosal-associated invariant T cells. (A-F) Representative hematoxylin and eosin-stained sections of the two PLZF+ cases (cases 1 and 2) and a PLZF- ALCL case (case 3) are shown in panels A, C, and E, respectively. The corresponding PLZF staining is shown in panels B, D, and F. Tumor site, immunophenotype, and the TCR-α rearrangements observed are shown below the respective positive cases. Complex karyotype seen in case 1 is as follows: 71∼87,XXXX,t(1;3)(p36.3;q25),-3,-4,-5,-7,-8,-9,9,del(10)(p11.2p15)×2,del(11)(q21q25)×2,der(12)t(3;12)(q25;q24.3)×2,dup(12)(q13q22)x2,-13,-14,-15,-16,-17,i(17)(q10),-18,+mar1x2,+mar2[cp11]. Photomicrographs are taken at magnification ×500 for all panels.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/123/17/10.1182_blood-2014-02-555482/4/2742f1.jpeg?Expires=1725055261&Signature=MX5DSH7UgN7YHpISZ08OuN5AHvpRD~iVhtSS75NvDO-qF5NUHPGraUzKaU-ecoHHm9MAdYFrz750ZzC8OhPvFM6wrDMVGqK9Mg1klEoDWZVEAn~5C5GL7gPlSjafp4FrQOt2x1auzylY~esNDP5bhTLwV8vMlxdhyHi18dT35MwBJsytN1uMm5~vPJhCMN~dctWEgO8qwCt8gOIms5wRIjxoA-tjcgvf2kGWBmoxw7TBowPoZdBvE0O7cGp-LYQzsPGrRX~ouz9h1htapJZBLrFtbHOG38yW8yf-GjehkTScE4V0VjeacIi1vJBqqd3-Fo-r76-1030Uz6zIrLTsNQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
PLZF expression identifies PTCL arising from innate-like mucosal-associated invariant T cells. (A-F) Representative hematoxylin and eosin-stained sections of the two PLZF+ cases (cases 1 and 2) and a PLZF- ALCL case (case 3) are shown in panels A, C, and E, respectively. The corresponding PLZF staining is shown in panels B, D, and F. Tumor site, immunophenotype, and the TCR-α rearrangements observed are shown below the respective positive cases. Complex karyotype seen in case 1 is as follows: 71∼87,XXXX,t(1;3)(p36.3;q25),-3,-4,-5,-7,-8,-9,9,del(10)(p11.2p15)×2,del(11)(q21q25)×2,der(12)t(3;12)(q25;q24.3)×2,dup(12)(q13q22)x2,-13,-14,-15,-16,-17,i(17)(q10),-18,+mar1x2,+mar2[cp11]. Photomicrographs are taken at magnification ×500 for all panels.
