Figure 3
The mut-Stat3 mice show increased susceptibility to C rodentium infection. Survival (A) and weight (B) plots of WT and mut-Stat3 mice after receiving an oral dose of 5 × 109 CFU C rodentium. Bacterial load present in the distal colon was determined at 4, 9, and 14 days postinfection, (C) and in the spleen and liver 14 days postinfection (D). Splenic neutrophil and monocyte/ macrophage cell numbers were determined 14 days postinfection (E). Data represents the cumulative results of 3 independent experiments (n = 32 for WT and n = 28 for mut-Stat3).
