Survival prediction in AITL. (A) Prognostic model in a training set and validated on an independent validation set. The optimal model represents that cases with high B-cell signature and low monocytic signature show favorable outcome compared with other cases (P = .004). (B) AITL cases are arranged according to model score, which represents differences between averages expression of B-cell signature and monocytic/P53 signature (mean). (C) Representative case from the upper (4th) quartile of the model score showing fewer CD20+ cells, whereas in (D) cases in lower(2nd) quartile showed a higher number of CD20+ B cells.