(A) Proportion of cases and controls grouped according to the number of risk alleles carried, (B) Plot of the increasing ORs for MGUS with increasing number of risk alleles. (A) Distribution of risk alleles in controls (black) and MGUS cases (gray) for the seven loci rs6746082, rs1052501, rs10936599, rs2285803, rs4487645, rs4273077, and rs877529. (B) The ORs are relative to the median number of 7 risk alleles; vertical bars correspond to 95% confidence intervals. The distribution of risk alleles follows a normal distribution in both case and controls, with a shift toward a higher number of risk alleles in cases. Horizontal line denotes the null value (OR, 1.0).