Leukocytes are mobilized to the blood by twice daily administration of plerixafor in WHIM syndrome patients: early phase. Patients were given 0.01 mg/kg plerixafor subcutaneously twice per day, and a complete blood count was determined before and every 3 hours after the morning dose for 12 hours. Left panels show the WBC (solid circles) and ALC (open squares), and right panels show the ANC (solid squares) and AMC (open circles) plotted against time, where day 0 is the first day of drug administration. Time of plerixafor administration is marked with arrows at the top of each column (note that data are missing after the evening dose because blood counts were obtained only during the day). Data for each patient are arranged in rows and designated on the right. Note that data were obtained twice for P3 (a and b) because treatment was interrupted for clinical care.