Gene expression changes upon JMJD1C KD. (A-B) Classification of genes with significant change in expression in (A) SEM cells and (B) MLL-AF9 cells into Gene Ontologies describing cellular function (top) and molecular activity (bottom). (C-D) Enrichment of indicated gene sets in JMJD1C KD vs (C) control SEM or (D) MLL-AF9 cells as revealed by GSEA. NES, normalized enrichment score; q value, false discovery rate. See also supplemental Table 2 and supplemental Figure 4C.