Causes and consequences of splenectomy in ALPS-FAS. Outcomes for all 66 patients undergoing splenectomy are shown. Note that each blue bar represents the timeline of events in 1 patient’s lifetime, and all the bars are stacked from the oldest at the bottom to the youngest patient in the cohort at the top. All 6 deaths due to sepsis were seen in patients who underwent splenectomy at a younger age (<10 years).