Figure 2
Figure 2. Peripheral blood cytokines elevated in both patients. Peripheral blood samples were collected in both patients at predetermined time points; specific levels of 30 cytokines were quantified and compared with baseline (preinfusion) samples. Only cytokines that were elevated at least 10-fold over baseline at any time point are shown. Case 2 received granulocyte colony-stimulating factor (G-CSF) as part of standard-of-care therapy following the autologous stem cell transplant. Baseline (preinfusion) serum values of the 9 analytes shown in Case 1 were IL-6, 12.5 pg/mL; IL-15, 30.8 pg/mL; IL-5, 1.82 pg/mL; IFN-γ, 1.68 pg/mL; IL-1Rα, 245 pg/mL; interferon-inducible protein 10 (IP-10), 99.9 pg/mL; IL-2R, 322 pg/mL; monokine induced by gamma interferon (MIG/CXCL9), 30.7 pg/mL; and IL-8, 11.6 pg/mL. Baseline levels of all cytokines analyzed in the serum in Case 2 are detailed in the legend for Figure 4B. FGF, fibroblast growth factor; GM-CSF, granulocyte macrophage CSF; HGF, hepatocyte growth factor; MCP-1, monocyte chemoattractant protein 1; VEGF, vascular endothelial growth factor.

Peripheral blood cytokines elevated in both patients. Peripheral blood samples were collected in both patients at predetermined time points; specific levels of 30 cytokines were quantified and compared with baseline (preinfusion) samples. Only cytokines that were elevated at least 10-fold over baseline at any time point are shown. Case 2 received granulocyte colony-stimulating factor (G-CSF) as part of standard-of-care therapy following the autologous stem cell transplant. Baseline (preinfusion) serum values of the 9 analytes shown in Case 1 were IL-6, 12.5 pg/mL; IL-15, 30.8 pg/mL; IL-5, 1.82 pg/mL; IFN-γ, 1.68 pg/mL; IL-1Rα, 245 pg/mL; interferon-inducible protein 10 (IP-10), 99.9 pg/mL; IL-2R, 322 pg/mL; monokine induced by gamma interferon (MIG/CXCL9), 30.7 pg/mL; and IL-8, 11.6 pg/mL. Baseline levels of all cytokines analyzed in the serum in Case 2 are detailed in the legend for Figure 4B. FGF, fibroblast growth factor; GM-CSF, granulocyte macrophage CSF; HGF, hepatocyte growth factor; MCP-1, monocyte chemoattractant protein 1; VEGF, vascular endothelial growth factor.

Close Modal

or Create an Account

Close Modal
Close Modal