PRCP and vascular injury and repair. (A) Representative photomicrographs of injured femoral arteries from WT (n = 40 arteries), PRCP^gt/gt (n = 45), or combined PRCP^gt/gt/MRP-14^−/− (n = 23) mice stained for elastin 14 days after wire injury. (B) Quantitative morphometric analysis of intima:media area ratio in WT, PRCP^gt/gt, and combined PRCP^gt/gt/MRP-14^−/− arteries. Data represent individual artery analysis for 23 to 45 animals per group. *P < .05, ***P < .001 on a 1-way analysis of variance. Representative immunohistochemical photomicrographs assessing leukocyte accumulation (CD45-positive cells [C]) and cellular proliferation (Ki67-positive cells [D]) 14 days after wire injury in WT, PRCP^gt/gt, or combined PRCP^gt/gt/MRP-14^−/− mice. All images were obtained using a Leica DM 2000 microscope with a 40×/0.65 objective lens. The sizing bar included in each image indicates 50 μm.