Figure 3
Figure 3. Results of luciferase assays of OCT2 and OCT2 mutants. Two different isoforms of OCT2 were used as indicated. (A) Luciferase assays results in HEK293-T cells indexed to the vector control (FG9) and normalized to protein expression by densitometry. (B) Luciferase assays results in HEK293-T cells carrying stable knockdown of OCT1 indexed to the vector control (FG9) and normalized to protein expression by densitometry. (C) Immunoblot results for the data presented in (A). (D) Immunoblot results for the data presented in (B). (Please note that the anti-OCT2 antibody used does not recognize some of the OCT2 mutants well.)

Results of luciferase assays of OCT2 and OCT2 mutants. Two different isoforms of OCT2 were used as indicated. (A) Luciferase assays results in HEK293-T cells indexed to the vector control (FG9) and normalized to protein expression by densitometry. (B) Luciferase assays results in HEK293-T cells carrying stable knockdown of OCT1 indexed to the vector control (FG9) and normalized to protein expression by densitometry. (C) Immunoblot results for the data presented in (A). (D) Immunoblot results for the data presented in (B). (Please note that the anti-OCT2 antibody used does not recognize some of the OCT2 mutants well.)

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