Identification of novel mutations in OCT2 in FL. (A) Schema of the OCT2 protein domain structure, details of somatic mutations identified in OCT2 in FL, and a comparative alignment of OCT-2 amino acid residues across multiple species. Red, location of missense mutations; green, location of indel mutation. NTD, N-terminal domain; CTD, C-terminal domain. (B) OCT2 sequence traces of paired tumor (T) and normal (N) samples.