Identification of novel mutations in the linker HIST1H1 genes B-E in FL and their association with other recurrent gene mutations. Top: schema of the HIST1H1 protein domain structure. Middle: details of somatic mutations identified in HIST1H1B-E in FL and comparative alignment of HIST1H1B-E amino acid residues. Red, location of missense mutations; green, location of indel mutation. Bottom: schema of the co-occurrence of linker histone HIST1H1B-E mutations and mutations in other genes. Cases with mutations are highlighted in blue.