Infarct volumes after LAD occlusion following reperfusion in sham-operated mice, mice treated with vehicle, DNase I, rhADAMTS13, or a combination of DNase I with rhADAMTS13. (A) Representative TTC stains of transverse sections of the LV of the 5 experimental groups. Infarctions appear as white and are outlined with dotted lines. The surrounding white layers represent the pericardium and were not included in the analysis. (B) Myocardial infarct size (expressed as % of LV) measured at 24 hours after LAD occlusion. *P < .05, ***P < .001 (blue asterisks represent comparison with vehicle; black, between treated groups).