Cytokines that are aberrantly expressed in MF are known to be developmentally required or secreted by DCs and also targeted by ruxolitinib. G-CSF, granulocyte colony-stimulating factor; HGF, hepatocyte growth factor; INF, interferon; IP-10, interferon-inducible protein 10; MCP-1, monocyte chemoattractant protein 1; MIG, monokine induced by interferon-gamma; MIP-1a, macrophage inflammatory protein 1a; VEGF, vascular endothelial growth factor.