Monocytes from NOD-SCID mice engrafted with human AML express increased YM-1. (A) NOD-SCID mice were injected with AML cells from patients. After engraftment, bone marrow was harvested from the femurs, and the expression of YM-1 on murine monocytes (Ly6C⁺) was assessed by flow cytometry. (B) Increased percentage of YM-1 positive monocytes in NOD-SCID mice engrafted with human AML. NOD-SCID mice were injected with AML cells from patients. After engraftment, bone marrow was harvested from the femurs, and the percentage of YM-1⁺ Ly6C⁺ murine monocytes was assessed by flow cytometry (***P = .0001).