Fondparinux inhibits platelet-mediated angiogenic response. (A) Endothelial cell migration after exposure to the releasate from control, resting platelets (Plts) or platelets activated with 25 μM ADP or stimulation with MCF-7 cells after exposure to fondaparinux. (B) Quantification of branch points generated by the releasate from resting platelets or platelets activated with 25 μM ADP or stimulation with MCF-7 cells after exposure to fondaparinux. (C) Representative images of capillary tube formation generated from the releasate of resting platelets or platelets exposed to ADP or MCF-7 cells with or without fondaparinux. *P < .05. Bars represent 100 μM.