Ruxolitinib-treated mice show a delay in clearing adenovirus infection. (A) C57/BL6N mice were infected with 5 × 10⁶ plaque-forming units of AdLGO, a recombinant adenovirus expressing OVA, enhanced green fluorescent protein, and click-beetle luciferase, followed by vaccination with OVA/CpG or left unprimed as control. Mice were fed 6 hours before as well as 6 hours and 18 hours after vaccination ruxolitinib or the respective vehicle control. (B) Time course of bioluminescence measurements is shown on a logarithmic scale. Results are from 1 experiment (n = 5 per group) representative of 3. The significance is related to the vehicle control. *P < .1; **P < .01; ***P < .001.