Blood parameters in WT and pIpC-treated Mx1-C1 mice. (A) Red blood cells (RBC), hemoglobin (Hb), white blood cells (WBC) and platelets (PLT). The results represent the median values from 5 WT vs 5 Mx1-C1 males. *P < .01. (B) May-Grünwald Giemsa stain of peripheral blood smears from WT and Mx1-C1 mice. Representative platelets are indicated by arrowheads. Scale bars, 20 μm. (C) Dot plots of forward-light scattering vs FL1 (FITC–anti-CD41) profiles of PRP display of the entire population of platelet sizes in WT and Mx1-C1 mice. Insert boxes (red) indicate the CD41⁺ population of WT platelets. (D) Prolonged bleeding time in Mx1-C1 mice. Tail bleeding times of WT (n = 6) and Mx1-C1 (n = 9) mice were monitored visually.