Mean vadastuximab talirine ADC plasma concentration-time profiles. Cycle 1 arithmetic mean vadastuximab talirine ADC plasma concentration-time profiles after administration of the first dose of vadastuximab talirine at 10 μg/kg in combination with either azacitidine (10+Aza) or dectitabine (10+Dec). (n=x) represents the total number of subjects in each combination group. The LLOQ for the ADC assay is 5 ng/mL. 10+Aza = 10 µg/kg vadastuximab talirine plus azacitidine, 10+Dec = 10 µg/kg vadastuximab talirine plus decitabine.