OS at 2 y after UCBT for patients with acute myeloid leukemia, acute lymphoid leukemia, and myelodysplasia in Europe and North America. (A) Children (≤16 years) from Europe: UCBT period 1996-1999 (n = 142), OS: 37 ± 4%; 2000-2005 (n = 441), OS: 41 ± 2%; 2006-2011 (n = 749), OS: 54 ± 2%. (B) Children (≤16 y) from North America: UCBT period 1996-1999 (n = 276), OS: 45 ± 6%; 2000-2005 (n = 843), OS: 50 ± 3%; 2006-2011 (n = 993), OS: 56 ± 6%. (C) Adults from Europe: UCBT period 1996-1999 (n = 46), OS: 26 ± 6%; 2000-2005 (n = 339), OS: 37 ± 3%; 2006-2011 (n = 1595), OS: 36 ± 2%. (D) Adults from North America: UCBT period 1996-1999 (n = 87), OS: 22 ± 8%; 2000-2005 (n = 359), OS: 31 ± 4%; 2006-2011 (n = 1210), OS: 34 ± 3%.