Basal and phospho-AKT levels measured in SS patients. (A) Western blotting analysis for AKT performed in sorted CD4⁺ lymphocytes from 5 SS patients. Two representative HDs of 5 patients analyzed are shown. (B) Western blotting analysis for phospho-AKT of sorted CD4⁺ lymphocytes from 14 SS patients. Two representative HDs of 5 patients analyzed are shown. Because of the timing of patient recruitment, the gels were run at separate times and the lanes were composed for the figure.