The combination of G1HE, dbG, and CACCC is sufficient for the lineage-specific enhancer activity of the GdC region. (A) A comparison of the GFP histogram of the lineage-committed hematopoietic cells from the bone marrow of the G1B-GFP (line 392; black) and MG-GFP (line 20; gray) transgenic mice. The Ter119-positive erythroblasts, CD41-positive megakaryocytes, Gr1/Mac1-double positive granulocytes, and B220-positive B cells are derived from adult bone marrow. The CD4/8-double positive T cells are derived from the thymus. (B) A comparison of the relative GFP mean intensity of the lineage-committed hematopoietic cells between the MG-GFP line 19 (n = 6), line 20 (n = 5), and G1B-GFP line 392 (n = 8), with an equal transgene copy number (2 copies). Data are presented as the mean ± SD. The statistical significance of differences between G1B-GFP and MG-GFP transgenic mice are indicated (**P < .01; Student unpaired t test).