Fibrin deposition in adipose tissue in obesity. Immunohistochemical staining for fibrin in paraffin sections of adipose tissue, showing increased fibrin deposition (reddish-brown color) in obese mice (A,B) compared with lean mice (C). (D) Negative control staining without the primary anti-fibrin antibody. Slides were counterstained with hematoxylin. Original magnification in all panels, ×400.