Figure 5
Figure 5. Morphology and comparative TCR-γ clonality analysis in case 4. (A-B) Hematoxylin and eosin stain in 2 recurrent skin biopsies taken 4 years apart at the age of 20 and 24 years. Note that the first biopsy (A) shows a denser lymphoid infiltrate when compared with the second biopsy (B; A-B: original magnification ×100). (C) Higher magnification of the second biopsy reveals a discrete infiltrate surrounding blood vessels with bland morphology. (D) Some of the lymphoid cells are EBER positive (C-D: original magnification ×400). (E-F) Amplification of the CD3 region of the TCR-γ chain gene showed an identical monoclonal peak of 195 base pairs in both biopsies.

Morphology and comparative TCR-γ clonality analysis in case 4. (A-B) Hematoxylin and eosin stain in 2 recurrent skin biopsies taken 4 years apart at the age of 20 and 24 years. Note that the first biopsy (A) shows a denser lymphoid infiltrate when compared with the second biopsy (B; A-B: original magnification ×100). (C) Higher magnification of the second biopsy reveals a discrete infiltrate surrounding blood vessels with bland morphology. (D) Some of the lymphoid cells are EBER positive (C-D: original magnification ×400). (E-F) Amplification of the CD3 region of the TCR-γ chain gene showed an identical monoclonal peak of 195 base pairs in both biopsies.

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