Figure 5
Figure 5. HIF-1α stabilization enhances blood recovery after severe sublethal irradiation. (A) Timeline of DMOG/saline administration, irradiation, and follow-up during recovery. Time course of blood leukocytes (B), granulocytes (C; measured by flow cytometry on CD11b+ Ly6-G+ cells), erythrocytes (D), hemoglobin (E), and platelets (F) after 9.0 Gy of irradiation of C57BL/6 mice pretreated with saline or DMOG for 18 days. Dashed lines show levels of leukopenia, neutropenia, anemia, and thrombocytopenia. Data are shown as the means ± SD from 12 different mice per treatment group. Significance levels were calculated using a t test.

HIF-1α stabilization enhances blood recovery after severe sublethal irradiation. (A) Timeline of DMOG/saline administration, irradiation, and follow-up during recovery. Time course of blood leukocytes (B), granulocytes (C; measured by flow cytometry on CD11b+ Ly6-G+ cells), erythrocytes (D), hemoglobin (E), and platelets (F) after 9.0 Gy of irradiation of C57BL/6 mice pretreated with saline or DMOG for 18 days. Dashed lines show levels of leukopenia, neutropenia, anemia, and thrombocytopenia. Data are shown as the means ± SD from 12 different mice per treatment group. Significance levels were calculated using a t test.

Close Modal

or Create an Account

Close Modal
Close Modal